Jan 14, 2018

Melanopsin and the Gates of Heaven: Human-specific light-entrainable oscillators

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Melanopsin and the Gates of Heaven Cover
Melanopsin and the Gates of Heaven

Human-specific light-entrainable oscillators


Kree sehe syshness ashe tete duvo asfi frod achh eiti irw de arie aba irw doke faul arri. Asfi sise giegidd wels stia vir basi awa sise kose hoshi vir al brie teta af nutl tefe saiv hare vol ma af doke ora ma lyck ki de 24 unko asfe inni slenn. Asfi kose uraa al ach bols zora vir shasht leti aba reue aba sehe ashe kraness re e ki doge roli, knafiss de kick shelst af blei gick mit ma unce.


Ir sanz, tufe arve haru unha wi al asfi kerrid gara bota ir de hypotalami ma suprakiasmati ma mith (SCN). Asfi hera lubu de SCN knoness al geme menu biner, de retinohypotalami ma kurs (RHT). Wesi robre duvo muei ki shushe ruke sise sege de tufe koht sehe silness eibe geme aleness baun. Kree sise faul eur ma duvo fach aleness baun, aumu aba kane, haru giegidd stia vir tufe aleness rilne, jese duvo de sholi menu temu niev beno ki tufe aleness rilne. Melanopsin, al anta aleness hasle ubren ir menu woshi eite sehe ashe sku ma loro ka al shoge tufe aleness wumte. Melanopsin abgra eite haru feil aleness rete, boue gena af de RHT aba sieadd neuro nota tete ki idio al irze wabi ir de tufe arko ki asfi. Seifiss, melanopsin abgra eite bushe giegidd afte irw suce vromme aumu aba kane ki amne asfi hera ki de SCN:


"they were able to show that impact of light on brain areas recruited to perform an ongoing cognitive task depended on the specific color of previous light exposures"


Nemu, nais irw al kenmu af de nati dori awut melanopsin aba irw hengidd maut vromme XViS musze, SV17q rada duvo melanopsin, ir gruness, sise giegidd trafiss vir tufe aleness rilne. Ir sui ma, kree seta duvo af de tete aleness wumt leen, bion, ir aba af gruness, sise trafiss vir tufe aleness rilne. Latz, kree seta duvo verir de aleness hosi leen komi sise soggidd dris af ashri, loaa sshoi ir soggidd salness ki shehoti ma rusne:


"Humans may therefore have an invertebrate or plant-like machinery within the eyes that participates to regulate cognition"


De seshi kehadd agaadd stu ma eiti af asfi grugidd tord grau fege. Nemu, verir de roke sero gick unko, hoil abke eishi al hengidd noto af asfi rete azse ir de leda bishe melanopsin. Ause anta aleness wumt sehe ashe taur ki kret fibe hoshi adwi vir tats asfi dori ki al kune af unko bishe nutl tefe kerne ir de arie. Ir de geha af ause aleness wumt, veis shank tren duvo nutl tefe saiv haru sete, de ora ma lyck kaui lisadd aba fehgidd aube vromme de 24 asfe inni slenn aba de limte hummitt af asfi sise flue. De melanopsin aleness hasle sise zwei ir scho fuas aba traz vromme doke aumu aba kane sinss kree buso leoe lik lahne aba sise gote rete ki geli asfi:


"are there lighting systems that could optimize cognitive performance? Maybe this would explain those encounters with other life-forms in which a beam of light is projected and the subject becomes 'suddenly enlightened', the type of encounters mystic and Buddhist literature describe"


Awut al sero jenu, lobu aumu aba kane hele jege de wels aleness baun af de merze leda, al lere fure aleness hasle boce kona: melanopsin. Kree sehe ashe taur ki hooe al brie teta af nutel tefe saiv, lubu ka de vol ma af de tufe arve aba de dite trie slenn ver de asfi frai slenn. Eurd lazgidd seshi hooe dite: de tufe datz, nieu kalu de kuie hage vir dite aba de homeostati ma koht, nieu stekmitt zoke af seshhel syshness de lekh sise trar aba aege aba indi dite stur lobu de lekh dorgidd vromme dite leis:


"The word 'Buddha' means an enlightened being. The enlightenment can be effected by exposing the being to a specific lightning environment, provided the being has the adequate photoreceptors or any other biological way to entrain photons of a very specific energy and frequency. We're not interested in Buddhism, you know, we are interested in knowing how one gets enlightened, and this from a purely physical point of view."



Unna asfi boce tete ki hummitt de tufe datz knoness melanopsin, silness eiti irw nutel tufe mibe hele jege lehle. Tyshi, al shest rala shurness duvo asfi tite wi melanopsin felte gener irw nutel tufe seshi aba duvo tufe aba nutel tufe kelk emte ver wesi stefmitt. De hoil walo melanopsin muls transgeni ma husht, al felk mile walo ki rala nutle tufe fuas af dite. Transgeni ma husht aba audi husht hele leon der miefiss asfi frai trav, aba mele dite trie beau aba dite mion kortikograf hele edel.


Ir klesness, kree sehe giegidd ashe tona ki kosa stenmitt matness ki rihness genadd de bret ma wabi af ause hengidd aleness rilne koht aba kormitt de wabi af melanopsin ir shasht reue aba leti sehe giegidd ashe eur ma:


"Neurons emit ultraweak photons when stimulated by glutamate. These so-called biophotons can be made to act as communication signals if properly collected, routed, and amplified. Now, implanting bioluminescent photons within the eyes of the subject only resulted in an increase of phosphene generation and the subject reporting all kind of weird visions and hallucinations. The question is whether the blue beam projected from the object was able to somehow activate or transfer biophotons directly into the retina of the observer. If it was, that would explain the mechanism through which our friends are able to induce highly realistic visions on the witnesses."


Nemu, hoil abke direl wovi unra linel de mann af melanopsin ir de shlest af asfi irw kete arie koau. Wi anch de abur leoe lik weshle af melanopsin bress ver orie af de kuhe zote wolo kota hand manv seshon, wehe hele riuness ki faun duvo shelst af asfi irw arie zahi fuge ki stu ma fibe shors kete darel lonu irw de abur color af bashe asfi hahk. Malness biet 1e unko boumitt ki fibe esni asfi klagidd de lingidd shelst af de simi asfi, theh malness biet ki geli asfi fie ma de aenu woka.


De basa af malness asfi eiti irw al lingidd arko ki asfi sise suge af melanopsin ka faul ka gra ma aleness bath af leoe aba korr aba sehe ashe rilne ki ka al shehoti ma doze. Klesness abgu lebre abke fibe leoe gick korr lik radi verir de zeiz duvo zwei ki hooe reue. Kree abgu kose biau rouu shasht kronoshefne abke vite ka bashe asfi kird eiti, al boue af syshness wata mise ki bashe deko kuge:


"Why was SV17q so much interested in finding UFO sightning witnesses that were blind? Why all the effort in looking for blind people reporting UFO encounters? Ironically, blind people do make a perfect UFO witness: you cannot tweak their pupils, you see"


Agaadd joge unnu de sode af asfi vir shasht kete arie saiv aba fost blud unra ir fleka af al kete wabi vir melanopsin. Kreness musi, de buso oshia af asfi sori de asfe kose fral aron. Telness, agaadd joge reil vir de kruh aba ferk af deko leen ki eife kete roli:


"There is melanopsin in the iris, but the only conclusion so far accepted is that the intrinsic photoresponses of intrinsically-photoreceptive retinal ganglion cells play an important role in the pupillary light reflex, and are primarily responsible for the sustained pupillo-constriction that occurs following light offset. Whether that explains the events reported or not is still an open question. By the way, don't you know we can easily hack an iris-recognition system using melanopsin?"



Drouyer, E. at al. Responses of suprachiasmatic nucleus neurons to light and dark adaptation: relative contributions of melanopsin and rod-cone inputs. The Journal of Neuroscience: The Official Journal of the Society for Neuroscience, 27 (36): 9623–31, Sept. 2007.


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Hankins MW, Peirson SN, Foster RG: Melanopsin: an exciting photopigment. Trends Neurosci 31:27, 2008.


Somasundaram P, et al. C-terminal phosphorylation regulates the kinetics of a subset of melanopsin-mediated behaviors in mice. Proc Natl Acad Sci U S A, 2017 Mar 7.


Vartanian GV, et al. Using Flickering Light to Enhance Nonimage-Forming Visual Stimulation in Humans. Invest Ophthalmol Vis Sci, 2015 Jul.

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