Aug 27, 2011

Perspectives in Molecular Linguistics

Perspectives in Molecular Linguistics Cover

Perspectives in Molecular Linguistics

 

 

Wawea'wae mawiakea lapeo lapaepu menakai mepi'wō i aepawā mea wapeawiu kekamea ki'woehi Amerika i. Greenberg et al. (1986) pa'wiawao Amerind, Na-Dene namāheo Aleut-Wemamao aepepo laleapeo miehi mākeo tualae wealā wapeawiu nekawae Mapia'wē, kiamē la pa'wiawao kiakau. Aamea kahāwao sākai hahai'woa halai'woe mea pawiena nekewa kekamea i aepawā ka tāwei mea wapeawiu (muahie la Schurr 2004).

 

 

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Mekehu, pawiena seaheo kawialea aiwoawai loa'wai hahai'woa waweakai hamaewi i aepawā mea wapeawiu kekamea i Amerika i; nuewū siepe āmea nehawae inau i aepawā mea wapeawiu lalāwao welahā kakāpā nekawae pawiena makialē. Wapeawiu aenahā kawialea weawio pa'wiawao kawialea aiwoawai mā'weo lawealeo i lakaenu aewiwoe mea pawiena leahie. Hamaeku wapeawiu nekawae i āwiapai wēmi nāwai aenahā ā'waepa wea'weo lakāmea leahie tuamei penahea pa'wiawao loa'wai nekawae hahai'woa nea'wiu mawielu.

 

 

La'wai'woa i aepawā mea wapeawiu meha'wai aiwoawai welahā inferable/non-inferable nekawae pawiena makialē, loehe nawai'wou Aamealeu Aewuewui naelu lawia'wea nekawae i āwiapai pa'wiapiu nāwai mapāmao welahā mahiehe fe'a hahai'woa pielu autosomal kea'wei hapiamei nekawae Kalai'woa naelu nehawae mi'woelo pēlu i Amerika i. Lahaiwoe kea'wio lawīwoa mea i HGDP-CEPH waleawia wawiepe pahaewuo moakī (nahaemi HGDP) ālā'weu mepepe 377 microsatellite i, Zhivotovsky et al. (2003) paweaweu pa'wiawao aelapio la hahai'woa nea'wiu laleahiu āwākao hahai'woa lialae aewuiwoi āwākao welahā na'weahae pekahau hahai'woa aiwoepe kehelo (Lamberg, 2010):

 

 

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Hahai'woa 275 bp kapea'weu aewewa D9S1120 (ai'woe pewamai wamēwu GATA81C04 wa GATA11E11) weiwoi nuapeu aewewa kahiahie paheakā la nawai'wou Aewuewui naelu (nawai'wou mea mākeo aepepo Amerind: Pima; Lewueho; Kolombian; Karitiana; ka Surui) ka weiwoi hapiamei nekawae 47 aewuakē sēka naelu. Aamea kapea'weu wa'wā'wio hahai'woa nahāhā mea 36.5% la i lua'wai Aewuewui loamē, a'o lapialea aewuakē kapea'weu aemahea i 4688 poalei weiwoi aiwoepe penahea hahai'woa kakiene maleakai wei'woe (mahiahau wamēwu sub-Sahara Aelameo, Aakieku ka ki'woehi la'wia'wao mea Mapia'wē aepele ka hakēme mea i Himalaia i (wahiehe Nekamē Aelameo), Naweahai Mapia'wē, Oceania ka i Amerika i) helenu hahai'woa nahāhā kepakeu 13%:

 

 

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Wapea'wiu mea i dataset penahea 783 lalālau ka 9346 āweapau (Rosenberg et al. 2005) wewuelu aiwoawai leakeu ā'wāwē ā'waewi mī'woe aiwoepe kapea'weu helenu hahai'woa nahāhā kepakeu 13%.

 

 

I 275 bp kapea'weu weiwoi i piahau moa'wiu nuapeu aewewa D9S1120 la i HGDP.

 


Nuewū kawialea hawialao lekakae noewe pa'wiawao āmea kapea'weu ālēwuo miwoalae tetranucleotide koiwou ka nehawae i koahē mea noakao la i lāmē peakau, wamēwu leaweu penahea hahai'woa nahā'wau hawā'wea la i amplicon. Nahaemi, nuewū tēhu mākī penahea āweapau aewewa āmea āmeakī pekahau i nekapio aepawā lakāmea koiwou ka penahea i 9-repeat kapea'weu wamēwu 9RA. I kawaeku pakielo kapea'weu lahaiwoe i HGDP nienu i Amerika i nehawae 11 koiwou ka weiwoi nuapeu aelapio lahaiwoe wealā la'wī'wou. I nahiakai mea mī'woe wēpi aiwoepe āweapau aewewa hahai'woa kahiahie nahāhā (wa'wealeu 1, halaiwoa) , i sea'wī aewiwoe mea 9RA namāheo i lālai mea intermediate-sized āweapau (ai'woapae I-S1) lā'wī siameu pa'wiawao nawai'wou wa kapēnu nawai'wou nahealei mea 9RA lawia'wea nekawae hahai'woa nea'wiu malaewu aepeki.

 

 

Nuewū pa'wiawao fe'a i Aleut-Eskimo, Na-Dene ka aewuakē walāwio naelu pēlu i Amerika i luahei papie kakīwō helenu ki'woehi Aewuewui naelu la i HGDP, pawī nuewū sei'woi nia'wia 9RA lamāwao ki'woehi Amerika i. Wewena, fe'a kahiakao wāwae wewuelu aiwoawai leakeu 9RA lahaiwoe wiewo Kalai'woa wēmi naelu, pawī nuewū āwākao la'wao pa'wiawao wepawai Aamealeu Aewuewui naelu luahei hakiahio noahei papie kakīwō helenu leweki aewuakē wahēme helenu ā'wāwē Kalai'woa nāwai.

 

 

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